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CBD Research

CBD Oil For Inflammation – 4 Surprising Inflammatory Conditions



If you’ve read any of our content here at ULU, you’ll already know that CBD is a natural anti-inflammatory. It’s something we talk about a lot! However, what you might not be aware of is just how many common conditions and illnesses are actually related to the body’s inflammatory response. So, today we’re going to talk about CBD and inflammation. We’ll talk about why you should be taking CBD oil for inflammation, and 4 surprising inflammatory conditions.


Why take CBD oil for inflammation?

Before we jump into some surprising inflammatory illnesses, let’s look at why CBD is so great at targeting inflammation.

CBD acts as a boost to your Endocannabinoid System (ECS) – a complex cell-signalling system within our bodies. The ECS is responsible for maintaining homeostasis – the fine biological balance that keeps everything running optimally. The ECS also works through two types of receptors, CB1 and CB2. So, when you take CBD, it acts like a key to unlock these receptors, allowing the ECS to work properly.

But what about inflammation?

Well, according to a recent study, the activation of the CB2 receptor ‘ leads to a decrease in ROS and TNF-α levels, which reduces oxidative stress and inflammation.’ So, when you take CBD and it binds to your CB2 receptors, helping to regulate your body’s response to inflammation – helping to reduce and mitigate inflammatory conditions.




So, let’s take a look at 4 conditions you probably didn’t know were related to inflammation. We’ll also look at how taking CBD oil for inflammation can help with each of them.


1. Depression

Depression is one of the most common yet perhaps one of the most surprising inflammatory conditions. According to the Mental Health Foundation, depression is the most predominant mental health condition worldwide. They also estimate that the number of people in the UK currently experiencing a depressive disorder to be as high as 20%.

These statistics aren’t very surprising. It’s likely that you or someone you know suffers from this mental health condition. However, what you may not know is that depression is often associated with increased inflammatory activation of the immune system. 

In fact, depression is usually accompanied by increased markers of inflammation and an over-active inflammatory response. This can also be supported by the fact that most anti-depressants have an anti-inflammatory effect, and that their efficacy is simnifically reduced by high levels of inflammation in the body.

Therefore, as CBD is a natural anti-inflammatory, it can not only help to reduce depression through the reduction of inflammation levels, it can also make anti-depressants work more effectively!


2. Fatigue

Fatigue is defined as a lack of physical and/or mental energy that interferes with daily activities. Sufferers of fatigue often describe feeling drained and exhausted as well as experiencing increased physical sensitivity to pain and brain-fog which inhibits concentration.

In addition, fatigue is another condition that is associated with inflammation. As we’ve already mentioned, high levels of pro-inflammatory cytokines are a main cause of inflammatory conditions. They can also lead to ‘cytokine-infused sickness behaviour’ – an umbrella term for a variety of illnesses associated with increased cytokine levels. According to a study about fatigue and inflammation, “Cytokine-induced sickness behaviour is a syndrome characterised by decreased activity, depression, and loss of energy because of the increased circulating levels of pro-inflammatory cytokines.”

However, it’s not all bad news for the chronically fatigued. This is because CBD actually helps to reduce the production of pro-inflammatory cytokines caused by an immune response to inflammation. So, taking a high dose of CBD over a long-term period could actually help to boost energy levels and reduce fatigue.




3. Asthma

Asthma is a common chronic breathing problem, particularly in areas with high levels of air pollution or a high pollen count. It is caused by inflammation of breathing tubes and a chronic inflammatory response within the airways. It’s also characterised by an increased sensitivity to asthma triggers and a build-up of mucus. As a result, an asthma attack leaves the sufferer unable to breathe and unable to allow oxygen to flow to the brain.

So, naturally the link between CBD and inflammation once again comes into play here. A recent CBD and asthma trial found that cannabidiol was able to reduce both inflammatory and remodelling processes in asthma sufferers. (‘Remodelling’ refers to the structural changes that occur in both large and small airways.) This inflammation and remodelling is also something that occurs in allergy-induced asthma.

Therefore, when you take CBD oil for inflammation, you’re helping to limit inflammatory response as a result of allergies or asthma.


4. Migraines

Anyone who has experienced migraines knows how truly debilitating they can be. Much worse than a simple headache, migraines can come with nausea, sensory disturbances, vertigo and also extreme, chronic pain. In addition, migraine treatments and medications also come with a variety of unpleasant side-effects.

However, there is significant evidence to show that CBD can reduce both the severity of migraine symptoms as well as migraine frequency. This is because inflammation actually plays a significant role in migraines. Migraines are associated with elevated high-sensitive C-reactive protein (hsCRP) – especially in young adults and women. They’re also associated with – you guessed it – pro-inflammatory cytokines.

However, once again, taking CBD can help limit your body’s production of cytokines, as well as limiting inflammation from hsCRP. So, if you’re a migraine sufferer, you might want to consider taking CBD oil for inflammation.

For more information on how CBD can help with migraines, check out our recent article: 7 Reasons to Take CBD For Migraines According to Science.





How to use CBD oil for inflammation

If you’re affected by any of the conditions we’ve mentioned in this article, why not try CBD oil for inflammation?

However, it’s important to note that although there is a direct link between CBD and inflammation, cannabidiol is not a quick-fix or a miracle cure. To get the best results and experience real benefits, you’ll need to:

  • Buy high-quality CBD from a reputable company (Find out the red flags you should avoid when buying CBD)
  • Take high-strength CBD oil – we’re not confident anything below 5% CBD oil or 3mg CBD per dose will have any noticeable effects
  • Use your CBD oil for inflammation regularly, over a long-term period. Don’t expect to see any difference overnight
  • Try to take your dose at the same time each day – ideally once in the morning and once before you go to bed
  • Never use CBD to replace prescribed medications – never stop taking any medications without consulting your doctor


CBD and inflammation summary

The link between CBD and inflammation is undeniable. In this article we’ve covered 4 surprising conditions that are linked to the body’s inflammatory response.

Although, inflammation is also linked to a huge number of other conditions. We haven’t covered the more obvious conditions such as IBS, swelling, itching, allergic reactions, arthritis and many more. However, for the reasons we’ve mentioned in this article, CBD is also a great addition to treatment options for these illnesses too!

So, if you’re looking to try CBD oil for inflammation, why not shop our range of ULU premium, organic CBD? We only offer high-strength cannabidiol products that meet our high standards of quality and purity. So, you can give your body and your mind the star treatment they deserve! Perfect for inflammatory conditions as well as overall mental health and wellbeing!



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